World Vaccine Congress US 2025

July 21, 2025

Summary:

  • Protective immunity depends not just on antibody titers, but also on Fc effector functions that engage the immune system through phagocytosis, cytotoxicity, and complement activation.
  • Fc-mediated functions play a critical role in differentiating antibody quality, helping explain protection in the absence of high titers or neutralization.
  • Comprehensive profiling across diverse immune cell types provides a more accurate understanding of efficacy and safety for both vaccine candidates and therapeutic antibodies.
  • SeromYx’s high-throughput, antigen-specific assays and computational analytics offer powerful tools to identify correlates of protection and guide candidate selection.

Authors:  Lenny Moise, PhD.

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