Publications
Systems serology for evaluation of HIV vaccine trials
Ackerman ME, et al. Immunol Rev. 2017 Jan; 275(1): 262–270.
High-resolution definition of humoral immune response correlates of effective immunity against HIV
Alter G, Dowell KG, et al. Mol Syst Biol. 2018 Mar; 14(3): e7881.
Systems serology: profiling vaccine induced humoral immunity against HIV
Chung AW, et al. Retrovirology. 2017; 14: 57.
Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs
Francica JR, et al. Blood Adv. 2017 Nov 28; 1(25): 2329–2342.
Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys
Barouch DH, et al. Science. Author manuscript; available in PMC 2016 Jan 17.
Beyond binding: antibody effector functions in infectious diseases
Lu LL, et al. Nat Rev Immunol. 2018 Jan; 18(1): 46–61.
Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines
Chung AW, et al. Science Translational Medicine 19 Mar 2014: Vol. 6, Issue 228, pp. 228ra38
Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology
Chung AW, et al. Cell. 2015 Nov 5; 163(4): 988–998.
A Functional Role for Antibodies in Tuberculosis
Lu LL, et al. Cell. 2016 Oct 6; 167(2): 433–443.e14.
A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus
Bronwyn M. Gunn, et al. Cell Host Microbe. 2018 Aug 8; 24(2): 221–233.e5.
Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection
Erica Ollmann Saphire*, et al. Cell. 2018 Aug 9; 174(4): 938–952.e13.
Evaluation of a mosaic HIV 1 vaccine in a multicentre randomised double blind placebo controlled phase 1 2a clinical trial APPROACH and in rhesus monkeys.
Barouch DH, et al. Lancet. 2018 Jul 21; 392(10143): 232–243.
Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination.
Suscovich TJ, et. al. Science Translational Medicine. 2020 Jul; 12(553): eabb4757
Distinct Early Serological Signatures Track with SARS-CoV-2 Survival
Atyeo et al. Immunity (2020)
View from the Fc: Five Rules for mAb Development Risk Reduction
SeromYx Team (2024)