The Systems Serology Platform
The Systems Serology Platform
Systems Serology is a suite of bead- and plate-based assays linked to systems biology/machine learning algorithms that enable the collection and interpretation of population-level functional and biophysical antibody profiles.



Developed at the Ragon Institute, Systems Serology functional assays can evaluate and link characteristics that define polyfunctional protective responses, for both monoclonal and polyclonal antibodies
MULTI-SPECIES
Currently support human, murine, and NHP samples; other species on request.
ADAPTABLE
Easily adaptable to analyze antibody responses against any antigen, both known and unknown.
QUALITY
SeromYx is fully GCLP-accredited, and assays are conducted under GCLP defined standards, supported by reports detailing assay sensitivity, reproducibility and performance.
5-steps to Systems Serology Correlative Functional Assay Data
The Suite of 12 Functional Assays
Nine assays interrogate antibody function, and three assays describe antibody biophysical structure, linking the specified effector function(s) to the biophysical structure of the Fc region of the antibody. For more information on effector function and how the Fc region of antibodies drives it, please click here.
ADCP
antibody dependent cellular phagocytosis
ADCC
antibody dependent cellular cytotoxicity
ADNKA
antibody dependent NK cell activation
ADED
antibody dependent eosinophil degranulation
ADBD
antibody dependent basophil degranulation
ADCD
antibody dependent complement deposition
ADNP
antibody dependent neutrophil activation/phagocytosis
ADDCP
antibody dependent dendritic cell phagocytosis
ADMB
antibody dependent mucin binding
Fc Receptor Array
antigen-specific antibody Fc receptor binding
Antibody Glycosylation Analysis
antigen-specific glycosylation analysis
Antibody Subclassing & Isotyping
antigen-specific subclassing & isotyping
Let's Talk - Contact us today to discuss your project.